8 reported
According to a Wired report, Chinese vape manufacturers are selling products containing nicotine analogs, chemicals that mimic nicotine's effects, to circumvent US federal regulations. Flavored nicotine vapes are largely illegal in the US, but Chinese companies have found a new way to sidestep the law by using these little-studied compounds. Current regulations narrowly define what counts as nicotine, allowing these products to avoid FDA oversight. Animal studies have found that one popular variant, 6-methyl-nicotine, could be more potent and addictive than regular nicotine. Researchers first documented these vapes in the US market about three years ago, though tobacco companies have researched such compounds since the 1970s. The Trump administration's proposed budget for fiscal year 2027 includes a legislative proposal to expand the definition of nicotine to include these analogs, which would close the loophole.
What’s reported
Chinese manufacturers are selling vapes with nicotine analogs to avoid US federal tobacco rules.
Flavored nicotine vapes are largely illegal in the US, but sales have generated billions of dollars despite FDA efforts.
Congress closed a loophole for synthetic nicotine in 2022, but current regulations still narrowly define nicotine.
Animal studies suggest 6-methyl-nicotine may be more potent and addictive than regular nicotine.
A 2024 study found some nicotine analog vapes contained unlabeled ingredients like artificial sweeteners and cooling agents.
Researchers first documented nicotine analog vapes in the US about three years ago.
The Trump administration's proposed 2027 budget includes a legislative proposal to expand the definition of nicotine to include analogs.
Four states—California, Nebraska, Indiana, and Tennessee—have expanded their definitions of tobacco products to include nicotine-like chemicals.
Key figures
Robert Jackler, emeritus professor of head and neck surgery at Stanford University
Rich Marianos, former official with the US Bureau of Alcohol, Tobacco, Firearms and Explosives, executive director of the Tobacco Law Enforcement Network
Tim Sheehy, Republican senator from Montana
Sources: Wired