Blue Jays vs. Giants prediction: Over 7 runs favored by model
The Toronto Blue Jays and San Francisco Giants conclude a three-game interleague series Wednesday afternoon at Oracle Park. San Francisco won the opener 10-1, and Toronto evened the series with a 9-3 victory Tuesday. Dylan Cease (5-4, 2.79 ERA) starts for the Blue Jays against Logan Webb (5-6, 3.66 ERA), both 2026 MLB All-Stars. The Blue Jays are listed as -122 favorites, with an over/under of 7 runs. The SportsLine Projection Model, which simulates every game 10,000 times, projects 8.2 total runs and recommends betting the Over. The model notes that both previous games surpassed the total, and the Over has an 8-2 record in San Francisco’s last 10 interleague games. Webb allowed 7 earned runs and 11 hits over 3 innings in his last start, while Cease gave up 4 earned runs over 4 innings against the Giants in a 2025 start.
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Sources: CBS Sports
